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Patricia Krentcil : ウィキペディア英語版 | Tanning dependence
Tanning dependence is a rare syndrome where an individual appears to have a physical or psychological dependence on sunbathing or the use of tanning beds. The mechanism of dependence is unknown at this time. ==Medical evidence== In 2005, a group of dermatologists published a study showing that frequent tanners experience a loss of control over their tanning schedule, displaying a pattern of dependence similar to smokers and alcoholics. 〔M. Warthan, T. Uchida, R. Wagner, Jr. UV Light Tanning as a Type of Substance-Related Disorder. Archives of Dermatology, August 2005; vol 141: pp 963-966.〕 Biochemical evidence implicates opioidergic mechanisms in tanning dependence. When frequent tanners took an endorphin blocker in a 2006 study, they experienced severe withdrawal symptoms, while infrequent tanners experienced no withdrawal symptoms under the same conditions. 〔M. Kaur, A. Liguori, W. Lang, S. Rapp, A. Fleischer, Jr., S. Feldman. Induction of withdrawal-like symptoms in a small randomized, controlled trial of opioid blockade in frequent tanners. Journal of the American Academy of Dermatology, 54(4): p. 709-711, 2006〕
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